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Ausgewählte Literatur zum Thema Proliferations-assoziiertes Ki-67 Antigen (pKi-67):

(Diese Liste soll nach und nach ausgebaut, mit Links versehen werden und mit Kommentaren/ knappen Übersichten zum Inhalt versehen werden)

MCM2 -a promising marker for premalignant lesions of the lung: a cohort study

Dong-Feng Tan 1 , Joel A Huberman 1 , Andrew Hyland 1 , Gregory M Loewen 1, John SJ Brooks 1 , Amy F Beck 1 , Ivan T Todorov 2 and Gerold Bepler*1

Kurze Zusammenfassung:

Vergleich der Expression von MCM2 und Ki-67:

In langsam wachsenden (nicht entarteten) Zellen ist MCM2 signifikant höher exprimiert als pKi-67, weil diese Zellen oft längere G1-Phasen haben. In Zellen mit G1-Arrest geht der Nachweis von pKi-67 mit MIB-1 deutlich zurück

http://rana.lbl.gov/papers/Perou_PNAS_1999.pdf

http://www.munksgaard.dk/pdf/117pdf.nsf/all/432170/$FILE/odi0040311.pdf

http://www.med-rz.uni-sb.de/med_fak/pathologie/iap98/publikationen/Virchow_Apoptose.pdf

Eigene Publikationen zum Thema:

(Ich schicke Ihnen auf Anfrage gerne pdf-Versionen oder Kopien der Paper zu): EMAIL an mich: mduchrow :-) compuserve.de

J.Gerdes, Li Li, C.Schlüter, M.Duchrow, C.Wohlenberg, C.Gerlach, I.Stahmer, S.Kloth, E.Brandt, and H.D.Flad

Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67

Am. J. Pathol. 138, 1991: 867 - 873

C.Fonatsch, M.Duchrow, H.Rieder, C.Schlüter, and J.Gerdes

Assignment of the human Ki-67 gene (MKI67) to 10q25-qter

Genomics 11 (2), 1991: 467 - 477

J.Gerdes, C.Schlüter, M.Duchrow, Li Li, G.Key, C.Gerlach, M.Becker, and H.-D.Flad

Recent approaches to the characterization of the cell proliferation associated nuclear antigen that is defined by monoclonal antibody Ki-67

In: G.Kindermann, B.Lampe (Hrg.), Immunhistochemische Diagnostik gynäkologischer Tumoren, G.Thieme Verlag, 1992: 2 - 7

G.Key, F.Megetto, M.H.G.Becker, T.Al Saati, C.Schlüter, M.Duchrow, G.Delsol, and J.Gerdes
Immunobiochemical characterization of the antigen detected by monoclonal antibody IND.64: Evidence that IND.64 reacts with the cell proliferation associated nuclear antigen previously defined by Ki-67

Virchows Archiv B Cell Pathol. 62, 1992: 259 – 261

G.Cattoretti, M.H.G.Becker, G.Key, M.Duchrow, C.Schlüter, J.Galle, and J.Gerdes

Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwave processed formalin-fixed paraffin sections

Journal of Pathol. 168, 1992: 357 - 363

G.Key, M.H.G.Becker, B.Baron, M.Duchrow, C.Schlüter, H.-D.Flad, and J.Gerdes

New Ki-67-equivalent murine monoclonal antibodies (MIB 1-3) generated against bacterially expressed parts of the Ki-67 cDNA containing three 62 bp repetitive elements encoding for the Ki-67 epitope

Lab. Invest. 68, 1993: 629 - 636

C.Schlüter, M.Duchrow, C.Wohlenberg, M.H.G.Becker, G.Key, H.-D.Flad, and J.Gerdes

The Cell Proliferation-associated Antigen of Antibody Ki-67: A Very Large, Ubiquitous Nuclear Protein with Numerous Repeated Elements, Representing a New Kind of Cell Cycle-maintaining Proteins

J. Cell Biol. 123, 1993: 513 - 522

G.Key, J.L.Petersen, M.H.G.Becker, M.Duchrow, C.Schlüter, J.Askaa, and J.Gerdes

New antiserum against Ki-67 antigen suitable for double immunostaining of paraffin wax sections

J. Clin. Pathol. 46, 1993: 1080 ‑ 1084

M.Duchrow, J.Gerdes and C.Schlüter

The Proliferation-Associated Ki‑67 Protein: Definition in Molecular Terms

Cell Prolif. 27, 1994: 235 - 242

H.G.Kubbutat, G.Key, M.Duchrow, C.Schlüter, H.-D.Flad, and J.Gerdes

Epitope Analysis of antibodies recognizing the cell proliferation associated nuclear antigen previously defined by the antibody Ki-67 (Ki-67 protein)

J. Clin. Pathol 47, 1994: 524 - 528

M.Duchrow, C,Schlüter und J.Gerdes

Molekularbiologische Charakterisierung des proliferationsassoziierten Ki-67-Proteins

Focus MUL 11, 1994: 219 – 225

M.Duchrow, C.Schlüter, G.Key, M.H.G.Kubbutat, C.Wohlenberg, H.-D.Flad, and J.Gerdes

Cell proliferation-associated nuclear antigen defined by antibody Ki-67: a new kind of cell cycle-maintaining proteins

Archivum Immunologiae et Therapiae Experimentalis 43, 1995: 117 - 121

M.Duchrow, C.Schlüter, C.Wohlenberg, H.-D.Flad, and J.Gerdes

Molecular characterization of the gene locus of the human cell proliferation-associated nuclear protein defined by monoclonal antibody Ki-67

Cell prolif. 29, 1996: 1 – 12

R.Broll, C.Mahlke, R.Best, H.Schimmelpenning, M.W.Strik, T.Schiedeck, H.-P.Bruch, and M.Duchrow

Assessment of the proliferation index in gastric carcinomas with the monoclonal antibody MIB-1.

J Cancer Res Clin Oncol 124, 1998: 49‑54

M.Duchrow, S.Häsemeyer, R.Broll, H.-P.Bruch, and U.Windhövel
Assessment of proliferative activity in colorectal carcinomas by quantitative RT‑PCR.
Cancer invest 19, 2001: 596-604; IF= 1,850

M.Duchrow, M.H.H.Schmidt, M.Zingler, S.Anemüller, H.-P.Bruch, and R.Broll
Suppression of Cell Division by Ki-67 Antisense-RNA and Recombinant Protein
Cell Physiol Biochem 11, 2001: 331-338 ->Abstract online; IF= 3,059

M.Duchrow, U.Windhövel, T.Bethge, O.Schwandner, U.Markert, H.-P.Bruch und R.Broll
Kunststoffnetze aus Polypropylen beeinflussen das Wachstum humaner Zellen in vitro
- Eine experimentelle Studie -
CHIRURG 73: 154-158 (2002); IF= 0,848

M.H.H.Schmidt, R.Broll, H.-P.Bruch, and M.Duchrow
The proliferation marker pKi 67 becomes masked to MIB-1 staining after expression of its tandem repeats
HISTOCHEM CELL BIOL 118: 415-422 (2002); IF= 2,054

M.H.H.Schmidt, R.Broll, H.-P.Bruch, and M.Duchrow
Proliferation marker pKi-67 affects the cell cycle in a self-regulated manner
J CELL BIOCHEM 87: 334-341 (2002); IF= 2,530

M.Duchrow, T.Ziemann, H.-P.Bruch, and R.Broll
Colorectal carcinomas with high MIB-1 labeling indices but low pKi-67 mRNA levels correlate with a better prognostic outcome
HISTOPATHOLOGY 42: 566-574 (2003); IF= 2,869

M.H.H.Schmidt, R.Broll, H.-P.Bruch, O. Bögler and M.Duchrow

The proliferation marker pKi 67 organizes the nucleolus during the cell cycle depending on Ran and Cyclin B
J PATHOL 199: 18-27 (2003); IF= 4,536

T.Bubán T, M.H.H.Schmidt, R.Broll, P.Antal-Szalmás, M.Duchrow

Detection of mutations in the cDNA of the proliferation marker Ki-67 protein in four tumor cell lines
J Cell Biochem 91: 1280-1292 (2004); IF= 2,530

M.H.H.Schmidt, R.Broll, H.-P.Bruch, S.Finniss, O.Bögler and M.Duchrow

Proliferation marker pKi-67 occurs in different isoforms with various cellular effects
J Cell Biochem 91: 1280-1292 (2004); IF= 2,530

T.Ihmann, J.Liu, W.Schwabe, P.Häusler, D.Behnke, H.-P.Bruch, R.Broll, and M.Duchrow

High level mRNA quantification of proliferation marker pKi-67 is correlated with favorable prognosis in colorectal carcinoma
J Cancer Res Clin Onc (2004; DOI 10.1007/s00432-004-0612-5); IF= 2,197

IF= Impact Faktor, SCI 2002)

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