I.     Original-Arbeiten:

1)        Duchrow M, Kohring GW, F.Giffhorn F. Virulence as a consequence of genomic instability of a novel temperate bacteriophage, ?RsG1, of Rhodobacter sphaeroides. Arch Microbiol 142: 141-147 (1985); IF= 1,903

2)        Duchrow M, Giffhorn F. Physical map of the Rhodobacter sphaeroides bacteriophage phi RsG1 genome and location of the prophage on the host chromosome. J Bacteriol 169: 4410-4414 (1987); IF= 3,959

3)        Duchrow M, Heitefuss S, Kalkus J, Hoppert M, Giffhorn F Isolation and characterization of a virulent phage for Rhodobacter sphaeroides.
ARCH MICROBIOL 149: 476-479 (1988); IF= 1,903

4)        Fonatsch C, Duchrow M, Rieder H, Schluter C, Gerdes J. Assignment of the human Ki-67 gene (MK167) to 10q25-qter. GENOMICS 11: 476-477 (1991); IF= 3,483

5)        Gerdes J, Li L, Schlueter C, Duchrow M, Wohlenberg C, Gerlach C, Stahmer I, Kloth S, Brandt E, Flad HD. Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67. AM J PATHOL 138: 867-873 (1991); IF= 6,750

6)        Arnoldi J, Schlüter C, Duchrow M, Hübner L, Böttger EC, Flad HD Gerdes J Spezies-spezifischer Nachweis von Mycobacterium leprae am histologischen Material durch in-situ-Hybridisierung. CLIN LAB 38: 335 - 339 (1992); IF= 1,099

7)        Arnoldi J, Schluter C, Duchrow M, Hubner L, Ernst M, Teske A, Flad HD, Gerdes J, Bottger EC. Species-specific assessment of Mycobacterium leprae in skin biopsies by in situ hybridization and polymerase chain reaction.
LAB INVEST 66: 618-623 (1992); IF= 4,000

8)        Cattoretti G, Becker MH, Key G, Duchrow M, Schluter C, Galle J, Gerdes J. Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwave-processed formalin-fixed paraffin sections. J PATHOL 168: 357-363 (1992); IF= 4,536

9)        Key G, Meggetto F, Becker MH, al Saati T, Schluter C, Duchrow M, Delsol G, Gerdes J. Immunobiochemical characterization of the antigen detected by monoclonal antibody IND.64. Evidence that IND.64 reacts with the cell proliferation associated nuclear antigen previously defined by Ki-67.
VIRCHOWS ARCH 62: 259-262 (1992); IF= 2,045

10)    Key G, Petersen JL, Becker MH, Duchrow M, Schluter C, Askaa J, Gerdes J.
New antiserum against Ki-67 antigen suitable for double immunostaining of paraffin wax sections. J CLIN PATHOL 46: 1080-1084 (1993); IF= 2,549

11)    Key G, Becker MH, Baron B, Duchrow M, Schluter C, Flad HD, Gerdes J.
New Ki-67-equivalent murine monoclonal antibodies (MIB 1-3) generated against bacterially expressed parts of the Ki-67 cDNA containing three 62 base pair repetitive elements encoding for the Ki-67 epitope.
LAB INVEST 68: 629-636 (1993); IF= 4,000

12)    Schluter C, Duchrow M, Wohlenberg C, Becker MH, Key G, Flad HD, Gerdes J. The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins. J CELL BIOL 123: 513-522 (1993); IF= 12,522

13)    Thanhauser A, Reiling N, Bohle A, Toellner KM, Duchrow M, Scheel D, Schluter C, Ernst M, Flad HD, Ulmer AJ. Pentoxifylline: a potent inhibitor of IL-2 and IFN-gamma biosynthesis and BCG-induced cytotoxicity.
IMMUNOLOGY 80: 151-156 (1993); IF= 2,729

14)    Flad HD, Richter E, Schluter C, Duchrow M, Arnoldi J, Hahn M, Graf vB, Alvarenga AE, Gerdes J. Mycobacterium leprae DNA content, cellular and cytokine patterns in skin lesions of leprosy patients undergoing multidrug therapy (MDT). IMMUNOBIOLOGY 191: 388-394 (1994); IF= 1,319

15)    Mattern T, Thanhauser A, Reiling N, Toellner KM, Duchrow M, Kusumoto S, Rietschel ET, Ernst M, Brade H, Flad HD. Endotoxin and lipid A stimulate proliferation of human T cells in the presence of autologous monocytes.
J IMMUNOL 153: 2996-3004 (1994); IF= 7,014

16)    Kubbutat MH, Key G, Duchrow M, Schluter C, Flad HD, Gerdes J. Epitope analysis of antibodies recognising the cell proliferation associated nuclear antigen previously defined by the antibody Ki-67 (Ki-67 protein).
J CLIN PATHOL 47: 524-528 (1994); IF= 2,549

17)    Reiling N, Ulmer AJ, Duchrow M, Ernst M, Flad HD, Hauschildt S. Nitric oxide synthase: mRNA expression of different isoforms in human monocytes/ macrophages. EUR J IMMUNOL 24: 1941-1944 (1994); IF= 4,832

18)    Richter E, Duchrow M, Schluter C, Hahn M, Flad HD, Gerdes J Detection of Mycobacterium leprae by three-primer PCR.
IMMUNOBIOLOGY 191: 351-353 (1994); IF= 1,319

19)    Mattern T, Reich C, Duchrow M, Ansorge S, Ulmer AJ, Flad HD Antibody-induced modulation of CD26 surface expression.
IMMUNOLOGY 84: 595-600 (1995); IF= 2,729

20)    Richter E, Schluter C, Duchrow M, Hahn M, Rusch-Gerdes S, Galle J, Flad HD, Gerdes J. An improved method for the species-specific assessment of mycobacteria in routinely formalin-fixed and paraffin-embedded tissues.
J PATHOL 175: 85-92  (1995); IF= 4,536

21)    Toellner KM, Scheel-Toellner D, Sprenger R, Duchrow M, Trumper LH, Ernst M, Flad HD, Gerdes J. The human germinal centre cells, follicular dendritic cells and germinal centre T cells produce B cell-stimulating cytokines.
CYTOKINE 7: 344-354 (1995); IF= 2,374

22)    Broll R, Lembcke K, Stock C, Zingler M, Duchrow M, Schimmelpenning H, Strik M, Muller G, Kujath P, Bruch HP. Immunzytochemischer Nachweis von Tumorzellen im Knochenmark und der Peritoneallavage bei Patienten mit Magen- und kolorektalen Karzinomen.
LANGENBECKS ARCH CHIR 381: 51-58 (1996); IF= 1,295

23)    Duchrow M, Schluter C, Wohlenberg C, Flad HD, Gerdes J. Molecular characteri­zation of the gene locus of the human cell proliferation-associated nuclear protein defined by monoclonal antibody Ki-67. CELL PROLIF 29: 1-12 (1996); IF= 1,898

24)    Richter E, Greinert U, Kirsten D, Rusch-Gerdes S, Schluter C, Duchrow M, Galle J, Magnussen H, Schlaak M, Flad HD, Gerdes J. Assessment of mycobacterial DNA in cells and tissues of mycobacterial and sarcoid lesions.
Am J Resp Crit Care 153: 375-380 (1996); IF= 6,567

25)    Broll R, Schauer V, Schimmelpenning H, Strik M, Woltmann A, Best R, Bruch HP, Duchrow M. Prognostic relevance of occult tumor cells in lymph nodes of colorectal carcinomas: an immunohistochemical study.
DIS COLON RECTUM 40: 1465-1471 (1997); IF= 2,308

26)    Strik MW, Laus C, Duchrow M, Broll R, Bruch HP. Nachweis des angiogenen Zytokins Vascular Endothelial Growth Factor (VEGF) durch nicht radioaktive In-situ-Hybridisierung. ANAT ANZ 179: 559-562 (1997); IF= 0,300

27)    Broll R, Mahlke C, Best R, Schimmelpenning H, Strik MW, Schiedeck T, Bruch HP, Duchrow M. Assessment of the proliferation index in gastric carcinomas with the monoclonal antibody MIB 1.
J CANCER RES CLIN 124: 49-54 (1998); IF= 2,197

28)    Cao L, Duchrow M, Windhovel U, Kujath P, Bruch HP, Broll R. Expression of MDR1 mRNA and encoding P-glycoprotein in archival formalin-fixed paraffin-embedded gall bladder cancer tissues.
EUR J CANCER 34: 1612-1617 (1998); IF= 3,562

29)    Schiedeck TH, Christoph S, Duchrow M, Bruch HP. Detection of hL6-mRNA: new possibilities in serologic tumor diagnosis of colorectal carcinomas.
ZBL CHIR 123: 159-162 (1998); IF= 0,259

30)    Broll R, Stark A, Windhovel U, Best R, Strik MW, Schimmelpenning H, Schwandner O, Kujath P, Bruch HP, Duchrow M. Expression of p53 and mdm2 mRNA and protein in colorectal carcinomas.
EUR J CANCER 35: 1083-1088 (1999); IF= 3,562

31)    Broll R, Windhovel U, Schiedeck T, Duchrow M, Bruch HP. Immunocytochemical and molecular proof of disseminated tumor cells in bone marrow, peritoneal lavage, blood and regional lymph nodes. A review of the literature and own results.
ZBL CHIR 124: 286-291 (1999); IF= 0,259

32)    Cao L, Peng S, Duchrow M. Expression of P-glycoprotein in benign and malignant gallbladder neoplasms. ZHON ZHON LIU ZA ZHI. 21:119-121 (1999); IF= 0,300

33)    Schulte T, Duchrow M, Schiedeck T, Bruch HP.  Influence of fresh frozen plasma, red blood cell packs, and hydroxyethyl starch on phagocytosis of leukocytes- an in vitro model. INFUS THER TRANSFUS MED 27: 23-29 (2000); IF= 0,333

34)    Schwandner O, Schiedeck TH, Bruch HP, Duchrow M, Windhoevel U, Broll R. p53 and Bcl-2 as significant predictors of recurrence and survival in rectal cancer. EUR J CANCER 36: 348-356 (2000); IF= 3,562

35)    Schwandner O, Schiedeck TH, Bruch HP, Duchrow M, Windhoevel U, Broll R. Apoptosis in rectal cancer: prognostic significance in comparison with clinical histopathologic, and immunohistochemical variables.
Dis Colon Rectum 43: 1227-1236 (2000); IF= 2,308

36)    Broll R, Duchrow M, Oevermann E, Wellm C, Schwandner O, Schimmelpenning H, Roblick UJ, Bruch HP, Windhovel U. p53 autoantibodies in sera of patients with a colorectal cancer and their association to p53 protein concentration and p53 immunohistochemistry in tumor tissue.
Int J Colorectal Dis 16: 22-27 (2001); IF= 1,902

37)    Broll R, Erdmann H, Duchrow M, Oevermann E, Schwandner O, Markert U, Bruch HP, Windhovel U Vascular endothelial growth factor (VEGF)--a valuable serum tumour marker in patients with colorectal cancer?
EUR J SURG ONCOL 27: 37-42 (2001); IF= 1,392

38)    Duchrow M, Häsemeyer S, Broll R, Bruch HP. Assessment of proliferative activity in colorectal carcinomas by quantitative RT-PCR.
CANCER INVEST 19: 596-604 (2001); IF= 1,850

39)    Duchrow M, Schmidt MH, Zingler M, Anemuller S, Bruch HP, Broll R Suppression of Cell Division by pKi-67 Antisense-RNA and Recombinant Protein. CELL PHYSIOL BIOCHEM 11: 331-338 (2001); IF= 3,059

40)    Broll R, Bethge T, Windhovel U, Schwandner O, Markert U, Bruch HP, Duchrow M. Einfluss resterilisierter Kunststoffnetze aus Polypropylen auf das Wachstum humaner Fibroblasten. ZBL CHIR 127: 589-593 (2002); IF= 0,259

41)    Duchrow M, Windhovel U, Bethge T, Schwandner O, Markert U, Bruch HP, Broll R. Kunststoffnetze aus Polypropylen beeinflussen das Wachstum humaner Zellen in vitro. CHIRURG 73: 154-158 (2002); IF= 0,848

42)    Otto K, Duchrow M, Broll R, Bruch HP, Strik MW. Expression of vascular endothelial growth factor mRNA and protein in human chronic renal allograft rejection. TRANSPLANT PROC 34: 3134-3137 (2002); IF= 0,478

43)    Schmidt MH, Broll R, Bruch HP, Duchrow M. The proliferation marker pKi-67 becomes masked to MIB-1 staining after expression of its tandem repeats. HISTOCHEM CELL BIOL 118: 415-422 (2002); IF= 2,054

44)    Schmidt MH, Broll R, Bruch HP, Duchrow M. Proliferation marker pKi-67 affects the cell cycle in a self-regulated manner.
J CELL BIOCHEM 87: 334-341 (2002); IF= 2,530

45)    Uthoff SM, Duchrow M, Schmidt MH, Broll R, Bruch HP, Strik MW, Galandiuk S. VEGF isoforms and mutations in human colorectal cancer.
INT J CANCER 101: 32-36 (2002); IF= 4,056

46)    Wehkamp J, Fellermann K, Herrlinger KR, Baxmann S, Schmidt K, Schwind B, Duchrow M, Wohlschlager C, Feller AC, and Stange EF. Human beta-defensin 2 but not beta-defensin 1 is expressed preferentially in colonic mucosa of inflammatory bowel disease.
EUR J GASTROENTEROL HEPATOL 14: 745-752 (2002); IF= 1,337

47)    Wehkamp J, Schwind B, Herrlinger KR, Baxmann S, Schmidt K, Duchrow M, Wohlschlager C, Feller AC, Stange EF, Fellermann K. Innate immunity and colonic inflammation: enhanced expression of epithelial alpha-defensins.
DIG DIS SCI 47: 1349-1355 (2002); IF= 1,438

48)    Schmidt MH, Broll R, Bruch HP, Bögler O, Duchrow M. The proliferation marker pKi-67 organizes the nucleolus during the cell cycle depending on Ran and Cyclin B. J PATHOL 199: 18-27 (2003); IF= 4,536

49)    Jabs WJ, Theissing E, Nitschke M, Bechtel JF, Duchrow M, Mohamed S, Jahrbeck B, Sievers HH, Steinhoff J, Bartels C. Local generation of C-reactive protein in diseased coronary artery venous bypass grafts and normal vascular tissue. Circulation 108: 1428-1431 (2003); IF= 10,255

50)    Duchrow M, Ziemann T, Windhövel U, Bruch HP, Broll R. Colorectal carcinomas with high MIB-1 labeling indices but low pKi-67 mRNA levels correlate with a better prognostic outcome. HISTOPATHOLOGY 42: 566-574 (2003); IF= 2,869

51)    Bubán T, Schmidt M, Broll R, Antal-Szalmás P, Duchrow M.  Detection of mutations in the cDNA of the proliferation marker Ki-67 protein in four tumor cell lines. Cancer Genet Cytogen 149: 81-84 (2004); IF= 1,713

52)    Schmidt MH, Broll R, Bruch HP, Finniss S, Bögler O, Duchrow M. Proliferation marker pKi-67 occurs in different isoforms with various cellular effects.
J Cell Biochem 91: 1280-1292 (2004); IF= 2,530

53)    Ihmann T, Liu J, Schwabe W, Häusler P, Behnke D, Bruch HP, Broll R, Windhövel U, Duchrow M. High level mRNA quantification of proliferation marker pKi-67 is correlated with favorable prognosis in colorectal carcinoma.
J Cancer Res Clin Onc 130: 749-756 (2004); IF= 2,197

54)    Windhövel U, Haasper C, Duchrow M, Bruch HP, Broll R. Effect of Cyclooxygenase-2 Antisense Oligodeoxyribonucleotides in A-549 Lung Cancer Cells.
ANTICANCER RES 24(6): (in press 2004); IF= 1,447

55)    Broll R, Busch P, Duchrow M, Oevermann E, Schwandner O, Farke S, Bruch HP,  Windhovel U. Influence of thymidylate synthase and p53 protein expression on clinical outcome in patients with colorectal cancer.
Int J Colorectal Dis 20 (2005): 94-102; IF= 1,902

 

 

II.       Übersichtsartikel:

1)        Duchrow M, Gerdes J, Schluter C. The proliferation-associated Ki-67 protein: definition in molecular terms. CELL PROLIF 27: 235-242 (1994); IF= 2,197

2)        Duchrow M, Schluter C, Gerdes J. Molekularbiologische Charakterisierung des proliferationsassoziierten Ki-67-Proteins.
FOCUS MUL 11: 219-225 (1994); IF= 0,300

3)        Duchrow M, Schluter C, Key G, Kubbutat MH, Wohlenberg C, Flad HD, Gerdes J. Cell proliferation-associated nuclear antigen defined by antibody Ki-67: a new kind of cell cycle-maintaining proteins.
ARCH IMMUNOL THER EXP 43: 117-121 (1995); IF= 0,793

 

III.  Buchbeiträge:

1)        Gerdes J, Schlüter C, Duchrow M, Li L, Key G, Gerlach C, Becker M, Flad HD (1992) Recent approaches to the characterization of the cell proliferation associated nuclear antigen that is defined by monoclonal antibody Ki-67. In Kin­dermann G, Lampe B. (eds.), Immunhistochemische Diagnostik gynäkologischer Tumoren, G. Thieme Ver­lag: pp 2-7

 

IV   Publizierte Manuskripte

1)      Duchrow M, Ziemann T, Stolfa A, Windhövel U, Bruch HP, Broll R
In Situ-Hybridisierung und Immunhistologie des pro­lifera­tionsassoziierten Ki-67 Antigens an kolorektalen Tumoren. Chir Austriaca (Suppl 147), 1998: 44-45

2)      Broll R, Erdmann H, Windhövel U, Duchrow M, Strik MW (1998) Bestimmung der Vascular Endothelial Growth Factor (VEGF)-Konzentration im Serum von Patienten mit einem kolorektalen Karzinom. In Herfarth C, Rothmund M, Hartel W (eds.), Chirurgisches Forum für experimentelle und klinische Forschung. Springer (Berlin, Heidelberg): pp 315-318

3)      Broll R, Weschta M, Windhoevel U, Berndt S, Schwandner O, Roblick U, Schiedeck TH, Schimmelpenning H, Bruch HP, Duchrow M (2001) Prognostic significance of free gastrointestinal tumor cells in peritoneal lavage detected by immunocytochemistry and polymerase chain reaction. LANGENBECKS ARCH SURG 386: 285-292

4)      Duchrow M, Windhövel U, Markert U, Broll R (2001) Einfluß von Polypropylen-Netzen auf die Proliferation und Apoptose verschiedener humaner Zellkulturen. In Schönleben K, Neugebauer E, Hartel W (eds), Chirurgisches Forum für experimentelle und klinische Forschung. Springer (Berlin, Heidelberg): pp 195-198

5)      Bethge T, Duchrow M, Windhövel U, Broll R (2002) Inhibition des Wachstums humaner Fibroblasten durch resterilisierte Kunststoffnetze aus Polypropylen. In Siewert JR, Neugebauer E, Hartel W (eds.) Chirurgisches Forum für experimentelle und klinische Forschung. Springer (Berlin, Heidelberg): pp 173-175

6)      Duchrow M, Windhövel U, Markert U, Broll R (2001) Influence of polypropylene meshes on the proliferation and apoptosis of different human cell cultures. In ISBN 3-540-41718-4, Springer-Verlag (Berlin Heidelberg New York): pp 195-198

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